杜谦

  一、个人基本信息                                               

　　杜谦，男，1987年4月生，籍贯湖北仙桃，博士，讲师

  二、教育及工作经历

　　2009年6月毕业于西北农林科技大学动物医学专业，获农学学士学位；

　　2016年6月毕业于365.com基础兽医学专业，获农学博士学位；

　　2016年8月起在365.com从事教学科研工作，讲师。

  三、研究方向及主讲课程

　　动物病理学，主要从事猪圆环病毒2型致病机制研究

　　讲授《动物病理学》课程

　四、代表性论文

　　1. Qian Du#, Yong Huang#, Tongtong Wang, Xiujuan Zhang, Yu Chen, Beibei Cui, Delong Li, Xiaomin Zhao, Wenlong Zhang, Lingling Chang, Dewen Tong*. Porcine circovirus type 2 activates PI3K/Akt and p38 MAPK pathways to promote interleukin-10 production in macrophages via Cap interaction of gC1qR. Oncotarget. 2016 Apr 5;7(14):17492-507.

　　2. Delong Li, Yong Huang, Qian Du, Zhenyu Wang, Lingling Chan, Xiaomin Zhao, Dewen Tong*. CD40 Ligand and GMCSF Coexpression Enhance the Immune Responses and Protective Efficacy of PCV2 Adenovirus Vaccine. Viral Immunology. April 2016, 29(3): 148-158.

　　3.  Xiaomin Zhao, Xiangjun Song, Xiaoyuan Bai, Naijiao Fei, Yong Huang, Zhiming Zhao, Qian Du, Hongling Zhang, Liang Zhang, Dewen Tong*. miR-27b attenuates apoptosis induced by transmissible gastroenteritis virus (TGEV) infection via targeting runt-related transcription factor 1 (RUNX1). PeerJ. 2016. 4e1635.

　　4. Hongling Zhang, Yong Huang, Qian Du, Xiaomao Luo, Liang Zhang, Xiaomin Zhao, Dewen Tong*. Porcine parvovirus infection induces apoptosis in PK-15 cells through activation of p53 and mitochondria-mediated pathway. Biochem Bioph Res Co. 2015; 456(2):649-655.

　　5. Yong Huang, Na Xing, Zengguo Wang, Xiujuan Zhang, Xiaomin Zhao, Qian Du, Lingling Chang, Dewen Tong*. Ultrasensitive Detection of RNA and DNA Viruses Simultaneously Using Duplex UNDP-PCR Assay. Plos One. 2015; 10(11).

　　6. Wei Li, Yong Huang, Xiaomin Zhao, Wenlong Zhang, Feng Dong, Qian Du, Dewen Tong*. Swainsonine Induces Caprine Luteal Cells Apoptosis via Mitochondrial-Mediated Caspase-Dependent Pathway. Journal of Biochemical and Molecular Toxicology. 2014; 28(10):456-464.

　　7. Yong Huang, Xiujuan Zhang, Qian Du, Fengyu Wang, Xiaomin Zhao, Wenlong Zhang, Dewen Tong*. Preclinical Detection of Porcine Circovirus Type 2 Infection Using an Ultrasensitive Nanoparticle DNA Probe-Based PCR Assay. Plos One. 2014; 9(5).

　　8. Yong Huang, Feng Dong, Qian Du, Hongling Zhang, Xiaomao Luo, Xiangjun Song, Xiaomin Zhao, Wenlong Zhang, Dewen Tong*. Swainsonine Induces Apoptosis through Mitochondrial Pathway and Caspase Activation in Goat Trophoblasts. International Journal of Biological Sciences. 2014; 10(7):789-797.

　　9. Li Ding, Yong Huang, Qian Du, Feng Dong, Xiaomin Zhao, Wenlong Zhang, Xingang Xu, Dewen Tong*. TGEV nucleocapsid protein induces cell cycle arrest and apoptosis through activation of p53 signaling. Biochem Bioph Res Co. 2014; 445(2):497-503.

　　10. Yong Huang, Meng Shao, Xingang Xu, Xiujuan Zhang, Qian Du, Xiaomin Zhao, Wenlong Zhang, Yahui Lyu, Dewen Tong*. Evidence for different patterns of natural inter-genotype recombination between two PCV2 parental strains in the field. Virus Research. 2013; 175(1):78-86.

　　11. Yong Huang, Wei Li, Xiaomin Zhao, Li Ding, Gaoshui Yu, Feng Dong, Qian Du, Xingang Xu, Dewen Tong*. Swainsonine differentially affects steroidogenesis and viability in caprine luteal cells in vitro. Theriogenology. 2013; 80(1):41-49.

　　12. Yong Huang, Li Ding, Zhaocai Li, Meiling Dai, Xiaomin Zhao, Wei Li, Qian Du, Xingang Xu, Dewen Tong*. Transmissible gastroenteritis virus infection induces cell apoptosis via activation of p53 signalling. Journal of General Virology. 2013; 94:1807-1817.

　　13. Li Ding, Xiaomin Zhao, Yong Huang, Qian Du, Feng Dong, Hongling Zhang, Xiangjun Song, Wenlong Zhang, Dewen Tong*. Regulation of ROS in transmissible gastroenteritis virus-activated apoptotic signaling. Biochem Bioph Res Co. 2013; 442(1-2):33-37.

　　14. Li Ding, Yong Huang, Meiling Dai, Xiaomin Zhao, Qian Du, Feng Dong, Lili Wang, Ruichao Huo, Wenlong Zhang, Xingang Xu, Dewen Tong*. Transmissible gastroenteritis virus infection induces cell cycle arrest at S and G2/M phases via p53-dependent pathway. Virus Research. 2013; 178(2):241-251.

　　15. 陈禹，杜谦（共同第一），霍瑞超，王莉莉，童德文，黄勇. 猪圆环病毒2型ORF1、ORF2和ORF3原核表达和多克隆抗体的制备[J]. 中国兽医学报，2015，05:686-691.

　　

五、联系方式

　　地址：陕西省西安市杨陵示范区西农路22号365.com

　　邮编：712100

　　邮箱：dewey3600@nwsuaf.edu.cn；dewey3600@163.com。