周栋

作者:  来源:  发布日期:2016-04-25 浏览次数:

  一、个人基本信息

  周栋,男,1984年8月生,山东诸城人,中国党员,博士,365.com讲师,中国畜牧兽医学会高级会员(A060001636S),执业兽医师,中国微生物学会会员(S212700378M)。中国畜牧兽医学会兽医产科学分会会员,中国畜牧兽医学会兽医内科与临床诊疗学分会会员,中国畜牧兽医学会动物繁殖学分会会员。自入职以来先后获批国家自然科学基金青年基金项目(31702310)、中国博士后基金面上项目(2016M602883)、陕西省自然科学基金(2017JQ3010)等多项科研资助,总经费60余万元。

  二、教育及研究经历

  1. 2004.09-2008.07,山东农业大学动物医学专业,获得农学学士学位;

  2. 2008.09-2011.07,山东农业大学临床兽医学专业,获农学硕士学位(导师:刘建柱 教授);

  3. 2011.09-2015.07,中国农业大学临床兽医学专业,获农学博士学位(导师:王九峰 教授,朱要宏 副教授);

  4. 2015.09至今,365.com,讲师。

  三、研究方向

  (1)动物生殖内分泌;(2)动物生殖免疫;(3)微生物与免疫。

  主讲课程:本科生《兽医产科学》。

  四、科研项目

  1. 国家自然科学基金青年项目(非折叠蛋白反应在调控奶山羊子宫内膜上皮细胞募集与活化Treg的分子机制,31702310,24万,2018.01-2020.12,主持);

  2. 陕西省自然科学基金(山羊子宫内膜细胞的内质网应激反应对调节性T细胞功能作用的研究,2017JQ3010,5万元,2017.01-2018.12,主持);

  3. 中国博士后科学基金(生殖激素与子宫内膜细胞对子宫调节性 T 细胞功能的影响,2016M602883,5万元,2016.04-2018.04,主持);

  4. 2015年博士科研启动基金(蜕膜化过程中内质网应激对蜕膜 Treg 细胞应答的作用机理,Z109021611,20万元,2015.12-2018.12,主持);

  5. 中央学校基本科研业务专项经费(山羊子宫内膜细胞在胚胎附植期对子宫 Treg 细胞招募的影响,Z109021703,10万元,2016.01-2018-12,主持)。

  6. 国家自然科学基金(鼠李糖乳杆菌调节仔猪肠顶膜Cl-/OH-交换及肠上皮紧密连接的分子机制,31372493,80万元,2014.01-2017.12,主要参与人 2/10)

  7. 国家自然科学基金(UPR 在奶牛子宫内膜炎症反应调控中的作用及其机制,31772817,61万元,2018.01-2021.12,主要参与人,3/8)

  五、发表论文

  Zhou D, Zhu Y.H., Zhang W., Wang M.L, Fan W.Y, Song D., Yang G.Y, Jensen B.B., Wang J.F. Oral administration of a select mixture of Bacillus probiotics generates Tr1 cells in weaned F4ab/acR(-) pigs challenged with an F4(+) ETEC/VTEC/EPEC strain. Veterinary Research . 2015. 46:95.(中科院一区,IF="2.98)

  Qi C., Zhou D., Liu J., Cheng Z., Zhang L., Wang L., Wang Z., Yang D., Wang S., Chai T. Detection of Babesia divergens using molecular methods in anemic patients in Shandong Province, China. Parasitology Research. 2011. 109(1):241-245.(共同第一作者,IF="2.33)

  Yang DQ., Jiang TT., Lin PF., Chen HT., Wang L., Wang N., Zhao F., Tang KQ., Zhou D., Wang AH., Jin, YP. Apoptosis inducing factor gene depletion inhibits zearalenone-induced cell death in a goat Leydig cell line. reproductive toxicology. 2017. 67, 129-139.(IF="2.34)

  Wang XG., Lin P., Li Y., Xiang CX., Yin YL., Chen Z., Du Y., Zhou D., Jin YP., Wang, AH. Brucella suis Vaccine Strain 2 Induces endoplasmic reticulum stress that affects intracellular replication in goat trophoblast cells in vitro . Front Cell Infect Mi . 2016. 6 :19.(IF="4.30)

  Zhang W., Zhu Y.H., Zhou D., Wu Q., Song D., Dicksved J., WangJ.F. Oral administration of a select mixture of Bacillus probiotics affects the gut microbiota and goblet cell function in newly weaned MUC4 resistant pigs following Escherichia coli challenge. applied and environmental microbiology. 2016: 02747-16.(IF="3.86)

  Yang GY, Zhu YH, Zhang W, Zhou D, Zhai CC, Wang JF. Influence of orally fed a select mixture of Bacillus probiotics on intestinal T-cell migration in weaned MUC4 resistant pigs following Escherichia coli challenge. Vet. Res . 2016. 47:71. (SCI IF = 3.85)

  Diqi Yang, Wang L, Lin PF., Jiang TT., Wang N., Zhao F., Chen HT., Tang KQ., Zhou D., Wang AH., Jin YP. N. An immortalized steroidogenic goat granulosa cell line as a model system to study the effect of the endoplasmic reticulum (ER)-stress response on steroidogenesis. J Reprod Develop . 2016. 63(1):27-36

  Chen FL., Lin PF., Wang N., Yang DQ., Wen X., Zhou D., Tang KQ., LinPF., Wang AH., Jin YP Herp depletion arrests the S phase of the cell cycle and increases estradiol synthesis in mouse granulosa cells. J Reprod Develop . 2016. 62 (2), 159-166.

  Chen FL., Lin PF., Wang N., Yang DQ., Wen X., Zhou D., Wang AH., Jin YP. Herp depletion inhibits zearalenone-induced cell death in RAW 264.7 macrophages. Toxicol in Vitro , 2016. 32 , 115-122.

  Zhang W, Zhu YH, Yang JC, Yang GY, Zhou D, Wang JF A selected Lactobacillus rhamnosus strain promotes EGFR-independent Akt activation in an enterotoxigenic Escherichia coli K88-Infected IPEC-J2 cell model. PLoS One . 2015. 10:e0125717. (SCI IF = 4.02)

  Zhang F. J., Weng X. G., Wang J. F., Zhou D., Zhang W., Zhai C. C., Hou T.X., Zhu Y. H. Effects of temperature–humidity index and chromium supplementation on antioxidant capacity, heat shock protein 72, and cytokine responses of lactating cows. J Anim Sci, 2014. 92 (7), 3026-3034.

  Zhu Y.H., Li X.Q., Zhang W., Zhou D., Liu H.Y., Wang J.F. Dose-dependent effects of Lactobacillus rhamnosus on serum IL-17 production and intestinal T cell responses in pigs challenged with Escherichia coli . Appl Environ Microbiol. 2014. 80:1787-1798.

  Liu J.Z., Zhou D., Cheng Z.Q., Wang Z.Y., Wang L., Wang S.J., Yang D.B., Chai T.J., Development and evaluation of enzyme-linked immunosorbent assay based on recombinant inorganic pyrophosphatase gene antigen for the detection of Mycoplasma suis antibodies. Res Vet Sci 2012 93: 48-50.

  Li XQ, Zhu YH, Zhang HF, Yue Y, Cai ZX, Lu QP, Zhang L, Weng XG, Zhang FJ, Zhou D, Yang JC, Wang JF. Risks associated with high-dose Lactobacillus rhamnosus in an Escherichia coli model of piglet diarrhoea: intestinal microbiota and immune imbalances. PLoS One 2012; 7(7): e40666.

  Liu J.Z., Cheng Z.Q., Zhou D., Zhang L., Yan Z.G., Wang Z.Y., Yang D.B., Liu Y.X., Chai T.J. Synthesis, cloning, and expression of Mycoplasma suis inorganic pyrophosphatase gene using PCR-based accurate synthesis and overlap-extension PCR, and its immunogenicity analysis. Res Vet Sci 2011. 91:100-102.

  六、获得奖励

  2015年6月 获中国农业大学校级优秀毕业生;

  2013年6月 获中国农业大学优秀共产党员称号;

  2011年6月 获山东省省级优秀毕业生,山东农业大学优秀毕业生。

  七、联系方式

  电子邮箱:zhoudong1949@163.com

  微信:zhoudong1949

  通讯地址:陕西杨凌西农路22号365.com

  邮编:712100


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